ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8(+) T cell fates

Long-term immunity depends partly on the establishment of memory CD8(+) T cells. We identified a counterregulatory network between the homologous transcription factors ZEB1 and ZEB2 and the miR-200 microRNA family, which modulates effector CD8(+) T cell fates. Unexpectedly, Zeb1 and Zeb2 had recipro...

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Detalles Bibliográficos
Autores principales: Guan, Tianxia, Dominguez, Claudia X., Amezquita, Robert A., Laidlaw, Brian J., Cheng, Jijun, Henao-Mejia, Jorge, Williams, Adam, Flavell, Richard A., Lu, Jun, Kaech, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881466/
https://www.ncbi.nlm.nih.gov/pubmed/29449309
http://dx.doi.org/10.1084/jem.20171352

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