An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly

Polo-like kinase 4 (Plk4) initiates an early step in centriole assembly by phosphorylating Ana2/STIL, a structural component of the procentriole. Here, we show that Plk4 binding to the central coiled-coil (CC) of Ana2 is a conserved event involving Polo-box 3 and a previously unidentified putative C...

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Detalles Bibliográficos
Autores principales: McLamarrah, Tiffany A., Buster, Daniel W., Galletta, Brian J., Boese, Cody J., Ryniawec, John M., Hollingsworth, Natalie Ann, Byrnes, Amy E., Brownlee, Christopher W., Slep, Kevin C., Rusan, Nasser M., Rogers, Gregory C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881488/
https://www.ncbi.nlm.nih.gov/pubmed/29496738
http://dx.doi.org/10.1083/jcb.201605106

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