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Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells

Schwann cells respond to cyclic adenosine monophosphate (cAMP) halting proliferation and expressing myelin proteins. Here we show that cAMP signaling induces the nuclear shuttling of the class IIa histone deacetylase (HDAC)–4 in these cells, where it binds to the promoter and blocks the expression o...

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Detalles Bibliográficos
Autores principales:	Gomis-Coloma, Clara, Velasco-Aviles, Sergio, Gomez-Sanchez, Jose A., Casillas-Bajo, Angeles, Backs, Johannes, Cabedo, Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881490/ https://www.ncbi.nlm.nih.gov/pubmed/29472387 http://dx.doi.org/10.1083/jcb.201611150

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