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Centrobin controls primary ciliogenesis in vertebrates

The BRCA2 interactor, centrobin, is a centrosomal protein that has been implicated in centriole duplication and microtubule stability. We used genome editing to ablate CNTROB in hTERT-RPE1 cells and observed an increased frequency of monocentriolar and acentriolar cells. Using a novel monoclonal ant...

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Detalles Bibliográficos
Autores principales:	Ogungbenro, Yetunde Adesanya, Tena, Teresa Casar, Gaboriau, David, Lalor, Pierce, Dockery, Peter, Philipp, Melanie, Morrison, Ciaran G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881496/ https://www.ncbi.nlm.nih.gov/pubmed/29440264 http://dx.doi.org/10.1083/jcb.201706095

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