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Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

Integrin activation regulates adhesion, extracellular matrix assembly, and cell migration, thereby playing an indispensable role in development and in many pathological processes. A proline mutation in the central integrin β3 transmembrane domain (TMD) creates a flexible kink that uncouples the topo...

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Detalles Bibliográficos
Autores principales:	Sun, Hao, Lagarrigue, Frederic, Gingras, Alexandre R., Fan, Zhichao, Ley, Klaus, Ginsberg, Mark H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881498/ https://www.ncbi.nlm.nih.gov/pubmed/29535192 http://dx.doi.org/10.1083/jcb.201707055

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