Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells

Infection with Helicobacter pylori is known to decrease the level of glutathione in gastric epithelial cells and increase the production of reactive oxygen species (ROS), which can lead to DNA damage and the development of gastric cancer. Cation transport regulator 1 (CHAC1) has γ‐glutamylcyclotrans...

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Detalles Bibliográficos
Autores principales: Wada, Yuriko, Takemura, Kosuke, Tummala, Padmaja, Uchida, Keisuke, Kitagaki, Keisuke, Furukawa, Asuka, Ishige, Yuuki, Ito, Takashi, Hara, Yukichi, Suzuki, Takashige, Mimuro, Hitomi, Board, Philip G., Eishi, Yoshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881537/
https://www.ncbi.nlm.nih.gov/pubmed/29632819
http://dx.doi.org/10.1002/2211-5463.12402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881537/
https://www.ncbi.nlm.nih.gov/pubmed/29632819
http://dx.doi.org/10.1002/2211-5463.12402

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