Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration

High oxygen tension caused by neovascularization in the microenvironment of intervertebral discs (IVDs) is associated with the pathogenesis of IVD degeneration (IDD). Pre-mRNAs undergo alternative splicing (AS) to produce structurally and functionally diverse mRNA and proteins. However, the precise...

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Detalles Bibliográficos
Autores principales: Feng, Chencheng, Zhang, Yang, Yang, Minghui, Lan, Minghong, Huang, Bo, Liu, Huan, Zhou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881661/
https://www.ncbi.nlm.nih.gov/pubmed/29512703
http://dx.doi.org/10.3892/ijmm.2018.3523

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