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VEN-120, a Recombinant Human Lactoferrin, Promotes a Regulatory T Cell [Treg] Phenotype and Drives Resolution of Inflammation in Distinct Murine Models of Inflammatory Bowel Disease
BACKGROUND AND AIMS: Inflammatory bowel disease [IBD] is characterised by a disruption of immune homeostasis, which is tightly regulated to protect against harmful pathogens yet not react to commensal antigens. Animal studies indicate that regulatory T cells [Treg] modulate the immune response to pr...
Autores principales: | MacManus, Christopher F, Collins, Colm B, Nguyen, Tom T, Alfano, Randall W, Jedlicka, Paul, de Zoeten, Edwin F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881664/ https://www.ncbi.nlm.nih.gov/pubmed/28472424 http://dx.doi.org/10.1093/ecco-jcc/jjx056 |
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