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Reviewing the Utility of Two Species in General Toxicology Related to Drug Development
As part of the safety assessment of new drugs, the use of two species (a rodent and a nonrodent) for regulatory toxicology studies is the typical approach taken for small molecules. For biologics, species selection is dictated by pharmacological relevance, and single species toxicology packages (typ...
Autores principales: | Prior, Helen, Baldrick, Paul, de Haan, Lolke, Downes, Noel, Jones, Keith, Mortimer-Cassen, Elisabeth, Kimber, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881785/ http://dx.doi.org/10.1177/1091581818760564 |
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