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Transplantation of human matrix metalloproteinase-1 gene-modified bone marrow-derived mesenchymal stem cell attenuates CCL4-induced liver fibrosis in rats
It has been reported that bone marrow-derived mesenchymal stem cells (BMSCs) alleviated liver fibrosis. We investigated whether BMSCs transfected with human matrix metalloproteinase 1 (BMSCs/MMP1) would improve their therapeutic effect in liver fibrosis induced by carbon tetrachloride (CCl(4)) in ra...
Autores principales: | Du, Chao, Jiang, Mingde, Wei, Xiaolong, Qin, Jianpin, Xu, Hui, Wang, Yunxia, Zhang, Yong, Zhou, Dejiang, Xue, Hongli, Zheng, Shumei, Zeng, Weizheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881841/ https://www.ncbi.nlm.nih.gov/pubmed/29512750 http://dx.doi.org/10.3892/ijmm.2018.3516 |
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