Synergistic activation of ERK1/2 between A-fiber neurons and glial cells in the DRG contributes to pain hypersensitivity after tissue injury

BACKGROUND: Intense nociceptive signaling arising from ongoing injury activates primary afferent nociceptive systems to generate peripheral sensitization. ERK1/2 phosphorylation in dorsal root ganglion can be used to visualize intracellular signal activity immediately after noxious stimulation. The...

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Detalles Bibliográficos
Autores principales: Yamakita, Shunsuke, Horii, Yasuhiko, Takemura, Hitomi, Matsuoka, Yutaka, Yamashita, Ayahiro, Yamaguchi, Yosuke, Matsuda, Megumi, Sawa, Teiji, Amaya, Fumimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881964/
https://www.ncbi.nlm.nih.gov/pubmed/29592783
http://dx.doi.org/10.1177/1744806918767508

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