Cargando…

Downregulation of neuroligin1 ameliorates postoperative pain through inhibiting neuroligin1/postsynaptic density 95-mediated synaptic targeting of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor GluA1 subunits in rat dorsal horns

Neuroligin1 is an important synaptic cell adhesion molecule that modulates the function of synapses through protein–protein interactions. Yet, it remains unclear whether the regulation of synaptic transmission in the spinal cord by neruoligin1 contributes to the development of postoperative pain. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Ruijuan, Li, Huili, Li, Xueyang, Xue, Zhaojing, Sun, Yuqing, Ma, Danxu, Guan, Yun, Li, Junfa, Tian, Ming, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881971/
https://www.ncbi.nlm.nih.gov/pubmed/29592780
http://dx.doi.org/10.1177/1744806918766745