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The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, in which myelin and oligodendrocytes are the main targets recognized by inflammatory CD4(+) T cells reactive to myelin peptides. Regulatory CD4(+) T (Treg) cells normally keep homeostasis of the immune system by inhibiti...

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Detalles Bibliográficos
Autores principales: Kimura, Kimitoshi, Hohjoh, Hirohiko, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881976/
https://www.ncbi.nlm.nih.gov/pubmed/29623002
http://dx.doi.org/10.1177/1179069518764892