Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

BACKGROUND: Around 0.3% of newborns will develop autoimmunity to pancreatic beta cells in childhood and subsequently develop type 1 diabetes before adulthood. Primary prevention of type 1 diabetes will require early intervention in genetically at-risk infants. The objective of this study was to dete...

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Detalles Bibliográficos
Autores principales: Bonifacio, Ezio, Beyerlein, Andreas, Hippich, Markus, Winkler, Christiane, Vehik, Kendra, Weedon, Michael N., Laimighofer, Michael, Hattersley, Andrew T., Krumsiek, Jan, Frohnert, Brigitte I., Steck, Andrea K., Hagopian, William A., Krischer, Jeffrey P., Lernmark, Åke, Rewers, Marian J., She, Jin-Xiong, Toppari, Jorma, Akolkar, Beena, Oram, Richard A., Rich, Stephen S., Ziegler, Anette-G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882115/
https://www.ncbi.nlm.nih.gov/pubmed/29614081
http://dx.doi.org/10.1371/journal.pmed.1002548

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