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Identification of HLA-DRB1 association to adalimumab immunogenicity

Anti-drug antibody formation occurs with most biological agents across disease states, but the mechanism by which they are formed is unknown. The formation of anti-drug antibodies to adalimumab (AAA) may decrease its therapeutic effects in some patients. HLA alleles have been reported to be associat...

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Detalles Bibliográficos
Autores principales:	Liu, Mohan, Degner, Jacob, Davis, Justin Wade, Idler, Kenneth B., Nader, Ahmed, Mostafa, Nael M., Waring, Jeffrey F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882140/ https://www.ncbi.nlm.nih.gov/pubmed/29614084 http://dx.doi.org/10.1371/journal.pone.0195325

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