A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer

Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for endocrine resistance in breast cancer. We show that G...

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Detalles Bibliográficos
Autores principales: Horibata, Sachi, Rice, Edward J., Zheng, Hui, Mukai, Chinatsu, Chu, Tinyi, Marks, Brooke A., Coonrod, Scott A., Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882141/
https://www.ncbi.nlm.nih.gov/pubmed/29614078
http://dx.doi.org/10.1371/journal.pone.0194522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882141/
https://www.ncbi.nlm.nih.gov/pubmed/29614078
http://dx.doi.org/10.1371/journal.pone.0194522

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