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A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer
Discovering regulatory interactions between genes that specify the behavioral properties of cells remains an important challenge. We used the dynamics of transcriptional changes resolved by PRO-seq to identify a regulatory network responsible for endocrine resistance in breast cancer. We show that G...
Autores principales: | Horibata, Sachi, Rice, Edward J., Zheng, Hui, Mukai, Chinatsu, Chu, Tinyi, Marks, Brooke A., Coonrod, Scott A., Danko, Charles G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882141/ https://www.ncbi.nlm.nih.gov/pubmed/29614078 http://dx.doi.org/10.1371/journal.pone.0194522 |
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