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Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma
Entry of hepatitis C virus (HCV) into hepatocytes is a complex process that involves numerous cellular factors, including the scavenger receptor class B type 1 (SR-B1), the tetraspanin CD81, and the tight junction (TJ) proteins claudin-1 (CLDN1) and occludin (OCLN). Despite expression of all known H...
Autores principales: | Sekhar, Vandana, Pollicino, Teresa, Diaz, Giacomo, Engle, Ronald E., Alayli, Farah, Melis, Marta, Kabat, Juraj, Tice, Ashley, Pomerenke, Anna, Altan-Bonnet, Nihal, Zamboni, Fausto, Lusso, Paolo, Emerson, Suzanne U., Farci, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882150/ https://www.ncbi.nlm.nih.gov/pubmed/29538454 http://dx.doi.org/10.1371/journal.ppat.1006916 |
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