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Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling
Increasing evidence indicates that the Golgi apparatus plays active roles in cancer, but a comprehensive understanding of its functions in the oncogenic transformation has not yet emerged. At the same time, the Golgi is becoming well recognized as a hub that integrates its functions of protein and l...
Autores principales: | Luchsinger, Charlotte, Aguilar, Marcelo, Burgos, Patricia V., Ehrenfeld, Pamela, Mardones, Gonzalo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882166/ https://www.ncbi.nlm.nih.gov/pubmed/29614107 http://dx.doi.org/10.1371/journal.pone.0195401 |
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