Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells

As a topical cancer immunotherapy, the toll-like receptor 7 ligand imiquimod activates tumor regression via stimulation of immune cell infiltration and cytotoxic responses. Imiquimod also exerts direct pro-apoptotic effects on tumor cells in vitro, but a role for these effects in imiquimod-induced t...

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Detalles Bibliográficos
Autores principales: Patchett, Amanda L., Wilson, Richard, Charlesworth, Jac C., Corcoran, Lynn M., Papenfuss, Anthony T., Lyons, Bruce A., Woods, Gregory M., Tovar, Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882306/
https://www.ncbi.nlm.nih.gov/pubmed/29662615
http://dx.doi.org/10.18632/oncotarget.24634

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