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Analysis of the PI3K-AKT-mTOR pathway in penile cancer: evaluation of a therapeutically targetable pathway

OBJECTIVES: To determine whether phosphatidylinositol-4,5-bisphosphate 3- kinase, catalytic subunit alpha (PIK3CA) copy number gain is common and could prove a useful marker for the activation status of the PI3K-AKT-mTOR pathway in penile squamous cell carcinoma (PSCC). METHODS: Fresh frozen tissue...

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Detalles Bibliográficos
Autores principales:	Adimonye, Anthony, Stankiewicz, Elzbieta, Kudahetti, Sakunthala, Trevisan, Giorgia, Tinwell, Brendan, Corbishley, Cathy, Lu, Yong-Jie, Watkin, Nick, Berney, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882318/ https://www.ncbi.nlm.nih.gov/pubmed/29662627 http://dx.doi.org/10.18632/oncotarget.24688

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