Cargando…

Potential therapeutic targets of TP53 gene in the context of its classically canonical functions and its latest non-canonical functions in human cancer

In normal tissue, p53 protein has a wide range of functions involving cell homeostasis; its mutation, however, permits a carcinogenic acquisition of function. TP53 gene mutation is a major genomic aberration in various human cancers and is a critical event in the multi-step carcinogenesis process. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Toshimichi, Watanabe, Masahiko, Yamashita, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882331/
https://www.ncbi.nlm.nih.gov/pubmed/29662640
http://dx.doi.org/10.18632/oncotarget.24611

Ejemplares similares