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The p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound Healing
The S100A2 protein is an important regulator of keratinocyte differentiation, but its role in wound healing remains unknown. We establish epithelial-specific S100A2 transgenic (TG) mice and study its role in wound repair using punch biopsy wounding assays. In line with the observed increase in proli...
Autores principales: | Pan, Shin-Chen, Li, Che-Yu, Kuo, Chia-Yi, Kuo, Yi-Zih, Fang, Wei-Yu, Huang, Yu-Hsuan, Hsieh, Tzu-Chin, Kao, Hung-Ying, Kuo, Yuan, Kang, Ya-Rong, Tsai, Wan-Chi, Tsai, Sen-Tien, Wu, Li-Wha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882638/ https://www.ncbi.nlm.nih.gov/pubmed/29615682 http://dx.doi.org/10.1038/s41598-018-23697-5 |
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