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Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells

Etoposide (ETP) and anthracyclines are applied for wide anti-cancer treatments. However, the ETP-induced cardiotoxicity remains to be a major safety issue and the underlying cardiotoxic mechanisms are not well understood. This study is aiming to unravel the cardiotoxicity profile of ETP in compariso...

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Detalles Bibliográficos
Autores principales:	Nemade, Harshal, Chaudhari, Umesh, Acharya, Aviseka, Hescheler, Jürgen, Hengstler, Jan Georg, Papadopoulos, Symeon, Sachinidis, Agapios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	In Vitro Systems
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882643/ https://www.ncbi.nlm.nih.gov/pubmed/29397400 http://dx.doi.org/10.1007/s00204-018-2170-7

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