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Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models are essential tools for designing new strategies to prevent DN. C57Bl/6 (B6) mice are widely used for transgenic mouse models, but are relatively resistant to DN. This study aims to identify the most effective me...

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Detalles Bibliográficos
Autores principales:	Uil, Melissa, Scantlebery, Angelique M. L., Butter, Loes M., Larsen, Per W. B., de Boer, Onno J., Leemans, Jaklien C., Florquin, Sandrine, Roelofs, Joris J. T. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882654/ https://www.ncbi.nlm.nih.gov/pubmed/29615804 http://dx.doi.org/10.1038/s41598-018-23839-9

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