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Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes

Anteroposterior (AP) axis extension during gastrulation requires embryonic patterning and morphogenesis to be spatiotemporally coordinated, but the underlying genetic mechanisms remain poorly understood. Here we define a role for the conserved chromatin factor Gon4l, encoded by ugly duckling (udu),...

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Detalles Bibliográficos
Autores principales: Williams, Margot L. K., Sawada, Atsushi, Budine, Terin, Yin, Chunyue, Gontarz, Paul, Solnica-Krezel, Lilianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882663/
https://www.ncbi.nlm.nih.gov/pubmed/29615614
http://dx.doi.org/10.1038/s41467-018-03715-w