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Sensing the Stress: A Role for the UPR(mt) and UPR(am) in the Quality Control of Mitochondria

Mitochondria exist as compartmentalized units, surrounded by a selectively permeable double membrane. Within is contained the mitochondrial genome and protein synthesis machinery, required for the synthesis of OXPHOS components and ultimately, ATP production. Despite their physical barrier, mitochon...

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Detalles Bibliográficos
Autores principales: Callegari, Sylvie, Dennerlein, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882792/
https://www.ncbi.nlm.nih.gov/pubmed/29644217
http://dx.doi.org/10.3389/fcell.2018.00031