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Sensing the Stress: A Role for the UPR(mt) and UPR(am) in the Quality Control of Mitochondria
Mitochondria exist as compartmentalized units, surrounded by a selectively permeable double membrane. Within is contained the mitochondrial genome and protein synthesis machinery, required for the synthesis of OXPHOS components and ultimately, ATP production. Despite their physical barrier, mitochon...
Autores principales: | Callegari, Sylvie, Dennerlein, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882792/ https://www.ncbi.nlm.nih.gov/pubmed/29644217 http://dx.doi.org/10.3389/fcell.2018.00031 |
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