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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...

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Detalles Bibliográficos
Autores principales: McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882811/
https://www.ncbi.nlm.nih.gov/pubmed/29615613
http://dx.doi.org/10.1038/s41467-018-03730-x

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