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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers
To realize the full potential of immunotherapy, it is critical to understand the drivers of tumor infiltration by immune cells. Previous studies have linked immune infiltration with tumor neoantigen levels, but the broad applicability of this concept remains unknown. Here, we find that while this ob...
Autores principales: | McGrail, Daniel J., Federico, Lorenzo, Li, Yongsheng, Dai, Hui, Lu, Yiling, Mills, Gordon B., Yi, Song, Lin, Shiaw-Yih, Sahni, Nidhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882811/ https://www.ncbi.nlm.nih.gov/pubmed/29615613 http://dx.doi.org/10.1038/s41467-018-03730-x |
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