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Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma

The computational repositioning of existing drugs represents an appealing avenue for identifying effective compounds to treat diseases with no FDA-approved pharmacotherapies. Here we present the largest meta-analysis to date of differential gene expression in human vestibular schwannoma (VS), a debi...

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Detalles Bibliográficos
Autores principales: Sagers, Jessica E., Brown, Adam S., Vasilijic, Sasa, Lewis, Rebecca M., Sahin, Mehmet I., Landegger, Lukas D., Perlis, Roy H., Kohane, Isaac S., Welling, D. Bradley, Patel, Chirag J., Stankovic, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882888/
https://www.ncbi.nlm.nih.gov/pubmed/29615643
http://dx.doi.org/10.1038/s41598-018-23609-7