Cargando…

Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer

Malignant breast cancer remains a major health threat to women of all ages worldwide and epigenetic variations on DNA methylation have been widely reported in cancers of different types. We profiled DNA methylation with ERRBS (Enhanced Reduced Representation Bisulfite Sequencing) across four main st...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Ying, Lin, Jhih-Rong, Zhang, Quanwei, O’Brien, Kelly, Montagna, Cristina, Zhang, Zhengdong D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882905/
https://www.ncbi.nlm.nih.gov/pubmed/29615825
http://dx.doi.org/10.1038/s41598-018-24005-x