Entropic effect of macromolecular crowding enhances binding between nucleosome clutches in heterochromatin, but not in euchromatin

Sharp increase in macromolecular crowding induces abnormal chromatin compaction in the cell nucleus, suggesting its non-negligible impact on chromatin structure and function. However, the details of the crowding-induced chromatin compaction remain poorly understood. In this work, we present a comput...

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Detalles Bibliográficos
Autores principales: Oh, Inrok, Choi, Saehyun, Jung, YounJoon, Kim, Jun Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882907/
https://www.ncbi.nlm.nih.gov/pubmed/29615710
http://dx.doi.org/10.1038/s41598-018-23753-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882907/
https://www.ncbi.nlm.nih.gov/pubmed/29615710
http://dx.doi.org/10.1038/s41598-018-23753-0

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