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Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose
Vaccines offer an option to treat heroin and prescription opioid abuse and prevent fatal overdoses. Opioid vaccines elicit antibodies that block opioid distribution to the brain and reduce opioid-induced behavioral effects and toxicity. The major limitation to the translation of addiction vaccines i...
Autores principales: | Laudenbach, Megan, Baruffaldi, Federico, Robinson, Christine, Carter, Philipp, Seelig, Davis, Baehr, Carly, Pravetoni, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882912/ https://www.ncbi.nlm.nih.gov/pubmed/29615715 http://dx.doi.org/10.1038/s41598-018-23777-6 |
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