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Distinct Metabolic features differentiating FLT3-ITD AML from FLT3-WT childhood Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease with dismal response warranting the need for enhancing our understanding of AML biology. One prognostic feature associated with inferior response is the presence of activating mutations in FMS-like tyrosine kinase 3 (FLT3) especially occurrence...

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Detalles Bibliográficos
Autores principales: Stockard, Bradley, Garrett, Timothy, Guingab-Cagmat, Joy, Meshinchi, Soheil, Lamba, Jatinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882915/
https://www.ncbi.nlm.nih.gov/pubmed/29615816
http://dx.doi.org/10.1038/s41598-018-23863-9