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Bile Acids Increase Doxorubicin Sensitivity in ABCC1-expressing Tumour Cells

Tumour cells possess or acquire various mechanisms to circumvent the cytotoxic effects of chemotherapy drugs. One such mechanism involves the overexpression of ABC transporters that facilitate the extrusion of a variety of structurally distinct chemotherapy drugs from the cytoplasm into the extracel...

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Detalles Bibliográficos
Autores principales:	Chewchuk, Simon, Boorman, Tyler, Edwardson, Derek, Parissenti, Amadeo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882947/ https://www.ncbi.nlm.nih.gov/pubmed/29615646 http://dx.doi.org/10.1038/s41598-018-23496-y

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