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Morphometric analysis of spread platelets identifies integrin α(IIb)β(3)-specific contractile phenotype
Haemostatic platelet function is intimately linked to cellular mechanics and cytoskeletal morphology. How cytoskeletal reorganizations give rise to a highly contractile phenotype that is necessary for clot contraction remains poorly understood. To elucidate this process in vitro, we developed a morp...
Autores principales: | Lickert, Sebastian, Sorrentino, Simona, Studt, Jan-Dirk, Medalia, Ohad, Vogel, Viola, Schoen, Ingmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882949/ https://www.ncbi.nlm.nih.gov/pubmed/29615672 http://dx.doi.org/10.1038/s41598-018-23684-w |
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