Endothelial indoleamine 2,3-dioxygenase-1 regulates the placental vascular tone and is deficient in intrauterine growth restriction and pre-eclampsia

Indoleamine 2,3-dioxygenase-1 (IDO1) mediates the degradation of L-tryptophan (L-Trp) and is constitutively expressed in the chorionic vascular endothelium of the human placenta with highest levels in the microvasculature. Given that endothelial expression of IDO1 has been shown to regulate vascular...

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Detalles Bibliográficos
Autores principales: Zardoya-Laguardia, Pablo, Blaschitz, Astrid, Hirschmugl, Birgit, Lang, Ingrid, Herzog, Sereina A., Nikitina, Liudmila, Gauster, Martin, Häusler, Martin, Cervar-Zivkovic, Mila, Karpf, Eva, Maghzal, Ghassan J., Stanley, Chris P., Stocker, Roland, Wadsack, Christian, Frank, Saša, Sedlmayr, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883010/
https://www.ncbi.nlm.nih.gov/pubmed/29615752
http://dx.doi.org/10.1038/s41598-018-23896-0

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