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Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa
Understanding the processes driving parasite assemblages is particularly important in the context of zoonotic infectious diseases. Leptospirosis is a widespread zoonotic bacterial infection caused by pathogenic species of the genus Leptospira. Despite a wide range of animal hosts, information is sti...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883017/ https://www.ncbi.nlm.nih.gov/pubmed/29615623 http://dx.doi.org/10.1038/s41426-018-0059-4 |
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author | Dietrich, Muriel Gomard, Yann Lagadec, Erwan Ramasindrazana, Beza Le Minter, Gildas Guernier, Vanina Benlali, Aude Rocamora, Gerard Markotter, Wanda Goodman, Steven M. Dellagi, Koussay Tortosa, Pablo |
author_facet | Dietrich, Muriel Gomard, Yann Lagadec, Erwan Ramasindrazana, Beza Le Minter, Gildas Guernier, Vanina Benlali, Aude Rocamora, Gerard Markotter, Wanda Goodman, Steven M. Dellagi, Koussay Tortosa, Pablo |
author_sort | Dietrich, Muriel |
collection | PubMed |
description | Understanding the processes driving parasite assemblages is particularly important in the context of zoonotic infectious diseases. Leptospirosis is a widespread zoonotic bacterial infection caused by pathogenic species of the genus Leptospira. Despite a wide range of animal hosts, information is still lacking on the factors shaping Leptospira diversity in wild animal communities, especially in regions, such as tropical insular ecosystems, with high host species richness and complex biogeographical patterns. Using a large dataset (34 mammal species) and a multilocus approach at a regional scale, we analyzed the role of both host species diversity and geography in Leptospira genetic diversity in terrestrial small mammals (rodents, tenrecs, and shrews) and bats from 10 different islands/countries in the western Indian Ocean (WIO) and neighboring Africa. At least four Leptospira spp. (L. interrogans, L. borgpetersenii, L. kirschneri, and L. mayottensis) and several yet-unidentified genetic clades contributed to a remarkable regional Leptospira diversity, which was generally related to the local occurrence of the host species rather than the geography. In addition, the genetic structure patterns varied between Leptospira spp., suggesting different evolutionary histories in the region, which might reflect both in situ diversification of native mammals (for L. borgpetersenii) and the more recent introduction of non-native host species (for L. interrogans). Our data also suggested that host shifts occurred between bats and rodents, but further investigations are needed to determine how host ecology may influence these events. |
format | Online Article Text |
id | pubmed-5883017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-58830172018-04-06 Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa Dietrich, Muriel Gomard, Yann Lagadec, Erwan Ramasindrazana, Beza Le Minter, Gildas Guernier, Vanina Benlali, Aude Rocamora, Gerard Markotter, Wanda Goodman, Steven M. Dellagi, Koussay Tortosa, Pablo Emerg Microbes Infect Article Understanding the processes driving parasite assemblages is particularly important in the context of zoonotic infectious diseases. Leptospirosis is a widespread zoonotic bacterial infection caused by pathogenic species of the genus Leptospira. Despite a wide range of animal hosts, information is still lacking on the factors shaping Leptospira diversity in wild animal communities, especially in regions, such as tropical insular ecosystems, with high host species richness and complex biogeographical patterns. Using a large dataset (34 mammal species) and a multilocus approach at a regional scale, we analyzed the role of both host species diversity and geography in Leptospira genetic diversity in terrestrial small mammals (rodents, tenrecs, and shrews) and bats from 10 different islands/countries in the western Indian Ocean (WIO) and neighboring Africa. At least four Leptospira spp. (L. interrogans, L. borgpetersenii, L. kirschneri, and L. mayottensis) and several yet-unidentified genetic clades contributed to a remarkable regional Leptospira diversity, which was generally related to the local occurrence of the host species rather than the geography. In addition, the genetic structure patterns varied between Leptospira spp., suggesting different evolutionary histories in the region, which might reflect both in situ diversification of native mammals (for L. borgpetersenii) and the more recent introduction of non-native host species (for L. interrogans). Our data also suggested that host shifts occurred between bats and rodents, but further investigations are needed to determine how host ecology may influence these events. Nature Publishing Group UK 2018-04-04 /pmc/articles/PMC5883017/ /pubmed/29615623 http://dx.doi.org/10.1038/s41426-018-0059-4 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Dietrich, Muriel Gomard, Yann Lagadec, Erwan Ramasindrazana, Beza Le Minter, Gildas Guernier, Vanina Benlali, Aude Rocamora, Gerard Markotter, Wanda Goodman, Steven M. Dellagi, Koussay Tortosa, Pablo Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title | Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title_full | Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title_fullStr | Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title_full_unstemmed | Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title_short | Biogeography of Leptospira in wild animal communities inhabiting the insular ecosystem of the western Indian Ocean islands and neighboring Africa |
title_sort | biogeography of leptospira in wild animal communities inhabiting the insular ecosystem of the western indian ocean islands and neighboring africa |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883017/ https://www.ncbi.nlm.nih.gov/pubmed/29615623 http://dx.doi.org/10.1038/s41426-018-0059-4 |
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