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Systemic IGF-1 gene delivery by rAAV9 improves spontaneous autoimmune peripheral polyneuropathy (SAPP)

Spontaneous autoimmune peripheral polyneuropathy (SAPP) is a mouse model of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in non-obese diabetic (NOD) mice null for costimulatory molecule, B7-2 gene (B7-2(−/−)). SAPP is a chronic progressive and multifocal inflammatory and demyelin...

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Detalles Bibliográficos
Autores principales: Gao, Tong, Bogdanova, Nataliia, Ghauri, Sameera, Zhang, Gang, Lin, Jianxin, Sheikh, Kazim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883061/
https://www.ncbi.nlm.nih.gov/pubmed/29615658
http://dx.doi.org/10.1038/s41598-018-23607-9

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