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Calculation of 3D genome structures for comparison of chromosome conformation capture experiments with microscopy: An evaluation of single-cell Hi-C protocols

Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell variability in the organization and packaging of genomes. These single-cell methods, unlike their multi-cell counterparts, allow straightforward computation of realistic chromosome conformations that may...

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Detalles Bibliográficos
Autores principales: Lando, David, Stevens, Tim J., Basu, Srinjan, Laue, Ernest D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883084/
https://www.ncbi.nlm.nih.gov/pubmed/29431585
http://dx.doi.org/10.1080/19491034.2018.1438799

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