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Hafnia alvei: A new pathogen in open fractures

BACKGROUND: Deep infection following open both bone forearm fractures is a rare complication. Prophylactic antibiotic regimens are targeted at the most common pathogens, which include primarily Staph aureus followed by gram-negative bacteria. Hafnia alvei is an unusual pathogen that is rarely pathog...

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Autores principales: Litrenta, Jody, Oetgen, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883196/
https://www.ncbi.nlm.nih.gov/pubmed/29644313
http://dx.doi.org/10.1016/j.tcr.2017.01.019
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author Litrenta, Jody
Oetgen, Matthew
author_facet Litrenta, Jody
Oetgen, Matthew
author_sort Litrenta, Jody
collection PubMed
description BACKGROUND: Deep infection following open both bone forearm fractures is a rare complication. Prophylactic antibiotic regimens are targeted at the most common pathogens, which include primarily Staph aureus followed by gram-negative bacteria. Hafnia alvei is an unusual pathogen that is rarely pathogenic in humans and has never been reported as a cause of infection following open fracture. METHODS: We present a 12-year-old male with an open forearm fracture who developed a late deep infection. Cultures grew only Hafnia alvei. The patient was treated with debridement, placement of antibiotic beads, and ciprofloxacin. RESULTS: At 6 months following the initial debridement, the patient had no clinical evidence of infection and regained full function of the affected forearm without any residual deficits. CONCLUSIONS: This is the first report of deep infection following an open forearm fracture owing to Hafnia alvei, a pathogen rarely responsible for human infection.
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spelling pubmed-58831962018-04-11 Hafnia alvei: A new pathogen in open fractures Litrenta, Jody Oetgen, Matthew Trauma Case Rep Article BACKGROUND: Deep infection following open both bone forearm fractures is a rare complication. Prophylactic antibiotic regimens are targeted at the most common pathogens, which include primarily Staph aureus followed by gram-negative bacteria. Hafnia alvei is an unusual pathogen that is rarely pathogenic in humans and has never been reported as a cause of infection following open fracture. METHODS: We present a 12-year-old male with an open forearm fracture who developed a late deep infection. Cultures grew only Hafnia alvei. The patient was treated with debridement, placement of antibiotic beads, and ciprofloxacin. RESULTS: At 6 months following the initial debridement, the patient had no clinical evidence of infection and regained full function of the affected forearm without any residual deficits. CONCLUSIONS: This is the first report of deep infection following an open forearm fracture owing to Hafnia alvei, a pathogen rarely responsible for human infection. Elsevier 2017-01-18 /pmc/articles/PMC5883196/ /pubmed/29644313 http://dx.doi.org/10.1016/j.tcr.2017.01.019 Text en © 2017 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Litrenta, Jody
Oetgen, Matthew
Hafnia alvei: A new pathogen in open fractures
title Hafnia alvei: A new pathogen in open fractures
title_full Hafnia alvei: A new pathogen in open fractures
title_fullStr Hafnia alvei: A new pathogen in open fractures
title_full_unstemmed Hafnia alvei: A new pathogen in open fractures
title_short Hafnia alvei: A new pathogen in open fractures
title_sort hafnia alvei: a new pathogen in open fractures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883196/
https://www.ncbi.nlm.nih.gov/pubmed/29644313
http://dx.doi.org/10.1016/j.tcr.2017.01.019
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