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Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis

BACKGROUND: Dying cells after irradiation could promote the repopulation of surviving cancer cells leading to tumor recurrence. We aim to define the role of dying cells in promoting pancreatic cancer cells metastasis following radiotherapy. METHODS: Using the transwell system as the in vitro co-cult...

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Detalles Bibliográficos
Autores principales:	Chen, Xuelian, Zhang, Lirong, Jiang, Yujie, Song, Lian, Liu, Yanfang, Cheng, Fang, Fan, Xin, Cao, Xiongfeng, Gong, Aihua, Wang, Dongqing, Zhu, Haitao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883315/ https://www.ncbi.nlm.nih.gov/pubmed/29615080 http://dx.doi.org/10.1186/s13046-018-0726-2

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