Cargando…

Bitter melon extract ameliorates palmitate-induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 cells and high-fat/high-fructose-diet-induced fatty liver

BACKGROUND: Bitter melon (BM) improves glucose level, lipid homeostasis, and insulin resistance in vivo. However, the preventive mechanism of BM in nonalcoholic fatty liver disease (NAFLD) has not been elucidated yet. AIM & DESIGN: To determine the protective mechanism of bitter melon extract (B...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hwa Joung, Cui, Rihua, Choi, Sung-E, Jeon, Ja Young, Kim, Hae Jin, Kim, Tae Ho, Kang, Yup, Lee, Kwan-Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Open Academia 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883859/ https://www.ncbi.nlm.nih.gov/pubmed/30026676 http://dx.doi.org/10.29219/fnr.v62.1319

Ejemplares similares

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

Procyanidin B2 Alleviates Palmitic Acid-Induced Injury in HepG2 Cells via Endoplasmic Reticulum Stress Pathway
por: Li, Yi-Ming, et al.
Publicado: (2021)

PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells
por: Chen, Yunzhi, et al.
Publicado: (2023)

Natural Thiols, but Not Thioethers, Attenuate Patulin-Induced Endoplasmic Reticulum Stress in HepG2 Cells
por: Kim, Hye Mi, et al.
Publicado: (2021)

Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells
por: Kim, Ok-Kyung, et al.
Publicado: (2016)

Wild Bitter Melon Extract Regulates LPS-Induced Hepatic Stellate Cell Activation, Inflammation, Endoplasmic Reticulum Stress, and Ferroptosis
por: Ho, Chang-Hsun, et al.
Publicado: (2021)

Saponins from bitter melon reduce lipid accumulation via induction of autophagy in C. elegans and HepG2 cell line
por: Bai, Juan, et al.
Publicado: (2022)

Celecoxib-mediated activation of endoplasmic reticulum stress induces de novo ceramide biosynthesis and apoptosis in hepatoma HepG2 cells
por: Maeng, Hyo Jin, et al.
Publicado: (2017)

Effects of Apoptin-Induced Endoplasmic Reticulum Stress on Lipid Metabolism, Migration, and Invasion of HepG-2 Cells
por: Zhu, Yilong, et al.
Publicado: (2021)

Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells
por: Liu, Jing-Yi, et al.
Publicado: (2019)

Resveratrol alleviates FFA and CCl(4) induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress
por: Li, Fenghua, et al.
Publicado: (2017)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2
por: Yang, Xuerui, et al.
Publicado: (2009)

USP10 Alleviates Palmitic Acid-induced Steatosis through Autophagy in HepG2 Cells
por: Xin, Sheng-Liang, et al.
Publicado: (2023)

Stepwise Assembly of Fibrinogen Is Assisted by the Endoplasmic Reticulum Lectin-Chaperone System in HepG2 Cells
por: Tamura, Taku, et al.
Publicado: (2013)

Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells
por: Tong, Tuantuan, et al.
Publicado: (2018)

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model
por: Park, Jae-Yeo, et al.
Publicado: (2015)

Roles of endoplasmic reticulum stress and autophagy on H(2)O(2)-induced oxidative stress injury in HepG2 cells
por: Wu, Zhiming, et al.
Publicado: (2018)

Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells
por: Zhang, Bo, et al.
Publicado: (2022)

2,4,6-Trinitrotoluene Induces Apoptosis via ROS-Regulated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in HepG2 and Hep3B Cells
por: Liao, Hung-Yu, et al.
Publicado: (2017)

Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells
por: Cho, Hyunju, et al.
Publicado: (2013)

Lactiplantibacillus plantarum MG4296 and Lacticaseibacillus paracasei MG5012 Ameliorates Insulin Resistance in Palmitic Acid-Induced HepG2 Cells and High Fat Diet-Induced Mice
por: Won, Gayeong, et al.
Publicado: (2021)

Suberoylanilide hydroxamic acid upregulates histone acetylation and activates endoplasmic reticulum stress to induce apoptosis in HepG2 liver cancer cells
por: Yu, Lei, et al.
Publicado: (2019)

Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells
por: Hu, Huiling, et al.
Publicado: (2022)

Ameliorative effects of black ginseng on nonalcoholic fatty liver disease in free fatty acid–induced HepG2 cells and high-fat/high-fructose diet-fed mice
por: Park, Miey, et al.
Publicado: (2020)

Trinitrotoluene Induces Endoplasmic Reticulum Stress and Apoptosis in HePG2 Cells
por: Song, Li, et al.
Publicado: (2015)

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation
por: YIN, JIAJING, et al.
Publicado: (2015)

The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts
por: Yang, Hsiang-Yu, et al.
Publicado: (2022)

Effect of Carotenoids from Phaeodactylum tricornutum on Palmitate-Treated HepG2 Cells
por: Mayer, Claire, et al.
Publicado: (2020)

Anti-diabetic Effects of Ethanol Extract from Bitter Melon in Mice Fed a High-fat Diet
por: Yoon, Nal Ae, et al.
Publicado: (2017)

Transcriptome and metabolome changes induced by bitter melon (Momordica charantia)- intake in a high-fat diet induced obesity model
por: Reed, Dominique, et al.
Publicado: (2021)

Anti-obesity Activity of Ethanol Extract from Bitter Melon in Mice Fed High-Fat Diet
por: Ae Yoon, Nal, et al.
Publicado: (2019)

Data for differentially expressed microRNAs in saturated fatty acid palmitate-treated HepG2 cells
por: Yang, Won-Mo, et al.
Publicado: (2016)

Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells
por: Yu, Xian, et al.
Publicado: (2018)

Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells
por: Lu, Jing, et al.
Publicado: (2019)

Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells
por: Ardid-Ruiz, Andrea, et al.
Publicado: (2019)

Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
por: Rajan, Priyanka, et al.
Publicado: (2021)

Antioxidant Effect of Wheat Germ Extracts and Their Antilipidemic Effect in Palmitic Acid-Induced Steatosis in HepG2 and 3T3-L1 Cells
por: Liaqat, Humna, et al.
Publicado: (2021)

Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells
por: Zhang, Yongjie, et al.
Publicado: (2018)

Emodin, an Emerging Mycotoxin, Induces Endoplasmic Reticulum Stress-Related Hepatotoxicity through IRE1α–XBP1 Axis in HepG2 Cells
por: Park, Su Been, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mbljh6ru3k8bt468gah2q64kk9