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miRNA-431 Prevents Amyloid-β-Induced Synapse Loss in Neuronal Cell Culture Model of Alzheimer's Disease by Silencing Kremen1

Synapse loss is well regarded as the underlying cause for the progressive decline of memory function over the course of Alzheimer's disease (AD) development. Recent observations suggest that the accumulation of the Wnt antagonist Dickkopf-1 (Dkk1) in the AD brain plays a critical role in trigge...

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Detalles Bibliográficos
Autores principales: Ross, Sean P., Baker, Kelly E., Fisher, Amanda, Hoff, Lee, Pak, Elena S., Murashov, Alexander K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883862/
https://www.ncbi.nlm.nih.gov/pubmed/29643768
http://dx.doi.org/10.3389/fncel.2018.00087