Enantioselective cellular localisation of europium(iii) coordination complexes

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake o...

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Detalles Bibliográficos
Autores principales: Frawley, Andrew T., Linford, Holly V., Starck, Matthieu, Pal, Robert, Parker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883863/
https://www.ncbi.nlm.nih.gov/pubmed/29675151
http://dx.doi.org/10.1039/c7sc04422d
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author Frawley, Andrew T.
Linford, Holly V.
Starck, Matthieu
Pal, Robert
Parker, David
author_facet Frawley, Andrew T.
Linford, Holly V.
Starck, Matthieu
Pal, Robert
Parker, David
author_sort Frawley, Andrew T.
collection PubMed
description The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.
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spelling pubmed-58838632018-04-19 Enantioselective cellular localisation of europium(iii) coordination complexes Frawley, Andrew T. Linford, Holly V. Starck, Matthieu Pal, Robert Parker, David Chem Sci Chemistry The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis. Royal Society of Chemistry 2017-12-06 /pmc/articles/PMC5883863/ /pubmed/29675151 http://dx.doi.org/10.1039/c7sc04422d Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
spellingShingle Chemistry
Frawley, Andrew T.
Linford, Holly V.
Starck, Matthieu
Pal, Robert
Parker, David
Enantioselective cellular localisation of europium(iii) coordination complexes
title Enantioselective cellular localisation of europium(iii) coordination complexes
title_full Enantioselective cellular localisation of europium(iii) coordination complexes
title_fullStr Enantioselective cellular localisation of europium(iii) coordination complexes
title_full_unstemmed Enantioselective cellular localisation of europium(iii) coordination complexes
title_short Enantioselective cellular localisation of europium(iii) coordination complexes
title_sort enantioselective cellular localisation of europium(iii) coordination complexes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883863/
https://www.ncbi.nlm.nih.gov/pubmed/29675151
http://dx.doi.org/10.1039/c7sc04422d
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