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Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus

Autoantibodies binding to the extracellular domains of desmoglein (Dsg) 3 and 1 are critical in the pathogenesis of pemphigus by mechanisms leading to impaired function of desmosomes and blister formation in the epidermis and mucous membranes. Desmosomes are highly organized protein complexes which...

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Detalles Bibliográficos
Autores principales:	Vielmuth, Franziska, Spindler, Volker, Waschke, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883869/ https://www.ncbi.nlm.nih.gov/pubmed/29643851 http://dx.doi.org/10.3389/fimmu.2018.00485

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