Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

BACKGROUND: Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated genes. In this paper we examine whether the signal from Toll-like receptors [TLRs] is sustained for as long as t...

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Detalles Bibliográficos
Autores principales: Hume, David A, Underhill, David M, Sweet, Matthew J, Ozinsky, Adrian O, Liew, Foo Y, Aderem, Alan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC58839/
https://www.ncbi.nlm.nih.gov/pubmed/11686851
http://dx.doi.org/10.1186/1471-2172-2-11

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