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Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types

Cell-free DNA (cfDNA) is a circulating DNA of nuclear and mitochondrial origin mainly derived from dying cells. Recent studies have shown that cfDNA is a stress signaling DAMP (damage-associated molecular pattern) molecule. We report here that the expression profiles of cfDNA-induced factors NRF2 an...

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Detalles Bibliográficos
Autores principales: Kostyuk, Svetlana V., Porokhovnik, Lev N., Ershova, Elizaveta S., Malinovskaya, Elena M., Konkova, Marina S., Kameneva, Larisa V., Dolgikh, Olga A., Veiko, Vladimir P., Pisarev, Vladimir M., Martynov, Andrew V., Sergeeva, Vasilina A., Kaliyanov, Andrew A., Filev, Anton D., Chudakova, Julia M., Abramova, Margarita S., Kutsev, Serguey I., Izhevskaya, Vera L., Veiko, Nataliya N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883976/
https://www.ncbi.nlm.nih.gov/pubmed/29743966
http://dx.doi.org/10.1155/2018/1052413