Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov

Clinical trials generate gold standard medical evidence, but are often criticized for the lack of population representativeness. We performed a comparative meta-analysis of drug trials that focus on older adults (>= 65 years old) and adults (18 – 64 years old). The major finding is that a higher...

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Detalles Bibliográficos
Autores principales: He, Zhe, Langford, Aisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884139/
https://www.ncbi.nlm.nih.gov/pubmed/29295350
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author He, Zhe
Langford, Aisha
author_facet He, Zhe
Langford, Aisha
author_sort He, Zhe
collection PubMed
description Clinical trials generate gold standard medical evidence, but are often criticized for the lack of population representativeness. We performed a comparative meta-analysis of drug trials that focus on older adults (>= 65 years old) and adults (18 – 64 years old). The major finding is that a higher percentage of geriatric drug trials were terminated or withdrawn than that of adult drug trials.
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spelling pubmed-58841392018-04-04 Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov He, Zhe Langford, Aisha Stud Health Technol Inform Article Clinical trials generate gold standard medical evidence, but are often criticized for the lack of population representativeness. We performed a comparative meta-analysis of drug trials that focus on older adults (>= 65 years old) and adults (18 – 64 years old). The major finding is that a higher percentage of geriatric drug trials were terminated or withdrawn than that of adult drug trials. 2017 /pmc/articles/PMC5884139/ /pubmed/29295350 Text en http://creativecommons.org/licenses/by-nc/4.0/ This article is published online with Open Access by IOS Press and distributed under the terms of the Creative Commons Attribution Non-Commercial License 4.0 (CC BY-NC 4.0).
spellingShingle Article
He, Zhe
Langford, Aisha
Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title_full Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title_fullStr Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title_full_unstemmed Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title_short Comparative Analysis of Geriatric and Adult Drug Clinical Trials on ClinicalTrials.gov
title_sort comparative analysis of geriatric and adult drug clinical trials on clinicaltrials.gov
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884139/
https://www.ncbi.nlm.nih.gov/pubmed/29295350
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