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Dose-Dependent Relationship Between Metformin and Colorectal Cancer Occurrence Among Patients with Type 2 Diabetes—A Nationwide Cohort Study()()()
BACKGROUND: Increasing bodies of evidence suggest that metformin may be beneficial in the primary prevention of colorectal cancer (CRC), and a dose–response relationship has been reported. However, long-term epidemiological observations between the treatment period, cumulative dose, and intensity of...
Autores principales: | Chang, Yu-Tang, Tsai, Hsiang-Lin, Kung, Ya-Ting, Yeh, Yung-Sung, Huang, Ching-Wen, Ma, Cheng-Jen, Chiu, Herng-Chia, Wang, Jaw-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884217/ https://www.ncbi.nlm.nih.gov/pubmed/29524831 http://dx.doi.org/10.1016/j.tranon.2018.02.012 |
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